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Control samples of RNA and DNA sourced from various organisms. Applications include use as a control template in PCR, in the creation of nucleic acid libraries, as an amplification/detection control in diagnostic testing, and other molecular applications.
A σ receptor ligand with anticancer and antiviral activites binds to σ1 and σ2 receptors (Kis 13 and 0.28 nM respectively in MCF-7 cell membranes) selective for σ1 and σ2 receptors over hERG channels (Ki 1000 nM) inhibits growth of MCF-7 and multidrug-resistant MCF-7/adr cells (IC50s 25 and 15 nM respectively) decreases basal P-gp levels in the same cells reduces SARS-CoV-2 infectivity in Vero E6 cells (IC90 278 nM)
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